Author

Weldy V. Bonilla

University of Basel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:CITE-seq· 1

Frequent Co-Authors

Anna Lena KastneriD· 2 shared Anna‐Friederike MarxiD· 2 shared Daniel D. PinscheweriD· 2 shared Doron MerkleriD· 2 shared Ingrid WagneriD· 2 shared Karsten Stauffer· 2 shared Mirela Dimitrova· 2 shared Tiago Abreu-MotaiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Anna Lena KastnerORCID

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2 papers

Recent·Most cited

Chronic Infection Perturbs the Affinity Hierarchy of Antiviral B Cells

Mirela Dimitrova, Tiago Abreu-Mota, Jonas Fixemer, Weldy V. Bonilla, Anna‐Friederike Marx, Min Lu, Karen Tintignac, Anna Lena Kastner, Yusuf I. Ertuna, Marianna Florova, Matías Ciancaglini, Kerstin Narr, Karsten Stauffer, Julien Roux, Philippe Demougin, , Daniel D. Pinschewer

This study shows that chronic viral infection disrupts B cell affinity hierarchies by preferentially causing attrition of high-affinity B cells due to excessive antigen stimulation.

bioRxiv · Aug 21, 2025 · PreprintImmunology

Permanent lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

Anna Lena Kastner, Anna‐Friederike Marx, Mirela Dimitrova, Tiago Abreu-Mota, Yusuf I. Ertuna, Weldy V. Bonilla, Karsten Stauffer, Marco Künzli, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Daniel D. Pinschewer

This study introduces depletion-AAVs to permanently eliminate lymphocyte subsets in mice, showing B cells are critical for CD4 and CD8 T cell responses to chronic viral infection.

Immunity · Dec 24, 2024Peer-reviewedImmunology