Bing Su

This study shows B cells sustain Langerin+ cDC1s via LTβ and MMMs to support anti-viral CD8+ T cell responses during MCMV infection.

VPS34-IN1 inhibits cap-mediated translation and enhances STING-driven type-I IFN expression in human plasmacytoid DCs by altering SGK3 recruitment and STING degradation.

The paper maps telocyte subtypes along the intestinal crypt-villus axis using single-cell RNA sequencing and identifies their distinct gene expression profiles and potential functional roles.

This study identifies Cpa3-expressing precursors as the source of embryonic mast cells, independent of granulocyte-monocyte progenitors, using single-cell RNA sequencing and genetic fate mapping.

This study uses brain organoids to model HDLS, showing that CSF-1R mutations in microglia lead to metabolic changes and inflammation that impair neuronal cells.

The paper shows SubAB induces IFN-I in pDCs via STING activation and UPR, highlighting a novel mechanism of immune regulation.

The paper develops a pipeline to profile both host expression and microbial abundance from spatial transcriptomic data, demonstrating host-microbe interactions and method efficiency.

This study uses single-cell RNA sequencing to analyze immune responses in COVID-19 patients, identifying key immune cell changes and molecular pathways linked to disease severity.

The paper analyzes meta-transcriptomic data to identify gene expression and novel conserved sub-genomic RNAs in SARS-CoV-2 and MERS-CoV, revealing new peptides with potential functional roles in viral virulence.