Probing Biomass Precursor Synthesis as a Key Factor in Microbial Adaptation to Unadapted Carbon Sources
Jingyi Cai, Jiayu Liu, Fan Wei, Wenjun Wu, Wenqi Xu, Zhitao Mao, Qianqian Yuan, Hongwu Ma
This paper introduces a computational framework, AdaptUC, to predict metabolic engineering strategies for microbial adaptation to unadapted carbon sources, showing improved driving forces and reduced substrate requirements in case studies.
Research · Jan 1, 2025Peer-reviewedBioengineering