Qianqian Yuan

A synthetic biology toolkit for interrogating plasmid-dependent methylotrophy and enhancing methanol-based biosynthesis of Bacillus methanolicus

This paper develops a synthetic biology toolkit for Bacillus methanolicus to study plasmid-dependent methylotrophy and enhance methanol-based biosynthesis of L-arginine.

Probing Biomass Precursor Synthesis as a Key Factor in Microbial Adaptation to Unadapted Carbon Sources

This paper introduces a computational framework, AdaptUC, to predict metabolic engineering strategies for microbial adaptation to unadapted carbon sources, showing improved driving forces and reduced substrate requirements in case studies.

FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

The paper introduces FROG analysis to standardize reproducibility assessments of genome-scale metabolic models, resulting in full reproducibility of all tested models.

Memote: A community-driven effort towards a standardized genome-scale metabolic model test suite

Memote, open-source Python software, runs a community-maintained, partly scored test suite (consistency, biomass, annotations, optional experimental data) on SBML-encoded genome-scale metabolic models, once or through continuous integration.