Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells
Wentian Luo, Alison Burgess Hickman, Pavol Genzor, Rodolfo Ghirlando, Christopher M. Furman, Anna Menshikh, Astrid D. Desiree Haase, Fred Dyda, Matthew H. Wilson
This study investigates how N-terminal phosphorylation and asymmetric transposon ends regulate piggyBac transposition in mammalian cells, revealing mechanisms that inhibit the process.
Nucleic Acids Research · Dec 7, 2022Peer-reviewedMolecular Biology