Author

Alison Burgess Hickman

National Institutes of HealthORCID 0000-0001-7666-0249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Fred DydaiD· 2 shared Alexandria Primich· 1 shared Anna Menshikh· 1 shared Astrid D. Desiree HaaseiD· 1 shared Christopher M. FurmaniD· 1 shared Matthew H. WilsoniD· 1 shared Pavol GenzoriD· 1 shared Raju MandaliD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Fred DydaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structure-based recasting of a mammalian DNA transpososomeas an obligate heterodimer

Raju Mandal, Alison Burgess Hickman, Rhea Desai, Alexandria Primich, Fred Dyda

The paper determines the structure of a hyperactive transpososome and engineers an obligate heterodimeric system for targeted genomic integration.

bioRxiv · Jul 16, 2026 · PreprintMolecular Biology

Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells

Wentian Luo, Alison Burgess Hickman, Pavol Genzor, Rodolfo Ghirlando, Christopher M. Furman, Anna Menshikh, Astrid D. Desiree Haase, Fred Dyda, Matthew H. Wilson

This study investigates how N-terminal phosphorylation and asymmetric transposon ends regulate piggyBac transposition in mammalian cells, revealing mechanisms that inhibit the process.

Nucleic Acids Research · Dec 7, 2022Peer-reviewedMolecular Biology