Pavol Genzor

This study investigates how N-terminal phosphorylation and asymmetric transposon ends regulate piggyBac transposition in mammalian cells, revealing mechanisms that inhibit the process.

The paper identifies conserved rules for generating a single major piRNA 3'-end in flies and mice, revealing a hierarchy between length and sequence preferences.

This study uses bulk and single-cell assays to analyze gene expression, histone modifications, and chromatin features in ESCs transitioning to mesoderm lineages, identifying cis-regulatory elements and transcription factors involved in lineage specification.

The paper identifies two classes of piRNAs based on abundance and function in genome defense, showing that abundance determines functional effectiveness.