Author

Wenzhao Shi

Digital China Health (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:fine-mapping· 1 Organism:human· 1 Research Focus:polygenic risk· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Chia‐Yen CheniD· 2 shared Hailiang HuangiD· 2 shared Kuang LiniD· 2 shared Max LamiD· 2 shared Ruize Liu· 2 shared Tian GeiD· 2 shared Yen‐Chen Anne FengiD· 2 shared Zhenglin Guo· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Chia‐Yen ChenORCID

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2 papers

Recent·Most cited

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases

Kai Yuan, Ryan J. Longchamps, Antonio F. Pardiñas, Mingrui Yu, Tzu‐Ting Chen, Shu‐Chin Lin, Yu Chen, Max Lam, Ruize Liu, Yan Xia, Zhenglin Guo, Wenzhao Shi, Chengguo Shen, Mark J. Daly, Benjamin M. Neale, , Hailiang Huang

This paper introduces SuSiEx, a cross-population fine-mapping method that improves resolution and power by integrating data across ancestries, leading to more accurate identification of causal variants in complex traits and diseases.

Nature Genetics · Aug 26, 2024Peer-reviewedGenetic & Genomic Medicine

Improving Polygenic Prediction in Ancestrally Diverse Populations

Yunfeng Ruan, Kuang Lin, Yen‐Chen Anne Feng, Chia‐Yen Chen, Max Lam, Zhenglin Guo, Stanley Global Asia Initiatives, Yong Min Ahn, Kazufumi Akiyama, Makoto Arai, Ji Hyun Baek, Wei J. Chen, Young‐Chul Chung, Gang Feng, Kumiko Fujii, , Tian Ge

This paper introduces PRS-CSx, a method that improves polygenic prediction across ancestrally diverse populations by integrating GWAS summary statistics and sharing genetic effects.

Nature Genetics · May 1, 2022Peer-reviewedGenetic & Genomic Medicine