Ultra-sensitive measurement of brain penetration mechanics and blood vessel rupture with microscale probes
Abdulmalik Obaid, Mina-Elraheb S. Hanna, Song-Wen Huang, Yu-Ting Hu, Omar Jáidar, William D. Nix, Jun Ding, Nicholas A. Melosh, Yu‐Wei Wu
The paper measures insertion mechanics and vascular responses of microscale neural probes in vivo, finding constant insertion force post-pia penetration and vessel displacement avoiding rupture at small scales.
Proceedings of the National Academy of Sciences · Mar 26, 2026Peer-reviewedNeuroscience