Chemokine Receptor 1 and its associated immune pathway are downregulated in SF3B1MT blood and non-blood cancers
Mahtab Dastpak, Hyunmin Kim, Christina L. Paraggio, Claudia E. Leonard, Shanye Yin, Binkai Chi, Kelsey W. Nassar, R. Grant Rowe, Zhonggang Hou, Jiuchun Zhang, Erin Frances Cohn, Na Young Yang, William Marion, Yosra Zhang, George Q. Daley, Robin Reed
The paper identifies downregulation of the CCR1 immune pathway in SF3B1-mutated cancers and links it to potential therapeutic targets.
bioRxiv · Mar 31, 2022 · PreprintMolecular Biology