Author

Binkai Chi

Harvard UniversityORCID 0000-0002-5433-3180Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Christina L. ParaggioiD· 2 shared Claudia E. Leonard· 2 shared Jiuchun ZhangiD· 2 shared Mahtab Dastpak· 2 shared Robin Reed· 2 shared Erin Frances Cohn· 1 shared George Q. DaleyiD· 1 shared Hyunmin KimiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Christina L. ParaggioORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 11, 2022

Three ALS genes regulate expression of the MHC class II antigen presentation pathway

Binkai Chi, Muhammet M. Öztürk, Christina L. Paraggio…·Robin Reed

The paper shows that ALS genes FUS, TAF15, and MATR3 regulate the MHC II antigen presentation pathway by downregulating HLA-DR and CD74 through loss of CIITA, with implications for immune system failure in ALS.

DOI 10.1101/2022.05.11.489680

humanproteomics

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Molecular BiologybioRxivPreprintMar 31, 2022

Chemokine Receptor 1 and its associated immune pathway are downregulated in SF3B1MT blood and non-blood cancers

Mahtab Dastpak, Hyunmin Kim, Christina L. Paraggio…·Robin Reed

The paper identifies downregulation of the CCR1 immune pathway in SF3B1-mutated cancers and links it to potential therapeutic targets.

DOI 10.1101/2022.03.31.485699

humanbulk RNA-seq

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