The stem loop 2 motif is a site of vulnerability for SARS-CoV-2
Valeria Lulla, Michal P. Wandel, Katarzyna Justyna Bandyra, Rachel Ulferts, Mary Wu, Tom Dendooven, Xiaofei Yang, Nicole Doyle, Stephanie Oerum, Rupert C. L. Beale, Sara M. O’Rourke, Felix Randow, Helena Jane Maier, William Scott, Yiliang Ding, , Ben F. Luisi
The paper identifies the stem loop 2 motif as a vulnerable site in SARS-CoV-2 that can be targeted by antisense oligonucleotides to inhibit replication and infection.
Journal of Virology · May 6, 2021Peer-reviewedMolecular Biology