Mutant p53 binds RNA to drive mitochondrial dysfunction
Wuyue Zhou, Alice Long, Cameron J. Douglas, Dalila Gallegos, James M. Burke, David W. C. MacMillan, Ezgi Hacisuleyman, Ciaran P. Seath
The paper identifies RNA binding by mutant p53 and shows it contributes to mitochondrial dysfunction through altered miRNA processing.
bioRxiv · Nov 12, 2025 · PreprintMolecular Biology