Cameron J. Douglas

The paper identifies SLK as a cancer-specific co-regulator of c-Myc using photoproximity labeling, showing it stabilizes c-Myc and drives tumorigenesis through splicing changes.

The paper identifies RNA binding by mutant p53 and shows it contributes to mitochondrial dysfunction through altered miRNA processing.

DeSciDe ranks gene lists using precedence and connectivity metrics to identify novel biological insights, revealing a new loss of function role for the H2A E92K mutation.

This study shows RNase L reduces antiviral proteins by inhibiting mRNA export and RNAPII-mediated transcription during flavivirus infection.

The paper introduces MesoMap, a mesoscale proximity labeling method to study chromatin occupancy changes, showing how HDAC inhibitors and the drug SR-1815 affect gene expression.

The paper identifies genetic modifiers of Huntington's disease somatic CAG repeat instability using CRISPR-Cas9 in HD knock-in mice, revealing new therapeutic targets.