David W. C. MacMillan

The paper introduces Map-uAA, a method for mapping protein microenvironments with residue-level precision using photocatalytic proximity labeling.

The paper identifies RNA binding by mutant p53 and shows it contributes to mitochondrial dysfunction through altered miRNA processing.

The paper uses photocatalytic proximity labeling to map HER2 interactions in breast cancer, identifying galectins and PTPRF as key players in resistance and signaling.

This paper introduces a photocatalytic method for drug target identification that improves signal-to-noise and enables detection of low-abundance targets.