Author

X. M. Shao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. Karchin· 2 shared V. Anagnostou· 2 shared A. B. Riemer· 1 shared A. Balan· 1 shared A. Omdahl· 1 shared A. Saeed· 1 shared A. V. Favorov· 1 shared B. Kaminow· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

R. Karchin

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Author profile →

3 papers

Recent·Most cited

SpliceMutr enables pan-cancer analysis of splicing-derived neoantigen burden in tumors

T. Palmer, M. D. Kessler, X. M. Shao, A. Balan, M. Yarchoan, N. Zaidi, T. Y. Lopez-Vidal, A. Saeed, J. Gore, N. Azad, E. Jaffee, A. V. Favorov, V. Anagnostou, R. Karchin, D. Gaykalova, , E. J. Fertig

SpliceMutr quantifies splicing-derived neoantigens across cancers, finding correlations with immune biomarkers and treatment response.

bioRxiv · May 26, 2023Cancer Biology

High-throughput prediction of MHC Class I and Class II neoantigens with MHCnuggets

X. M. Shao, R. Bhattacharya, J. Huang, I. K. A. Sivakumar, C. Tokheim, L. Zheng, D. HIrsch, B. Kaminow, A. Omdahl, M. Bonsack, A. B. Riemer, V. Velculescu, V. Anagnostou, K. Pagel, R. Karchin

The paper introduces MHCnuggets, a deep learning method for predicting MHC class I and II neoantigen binding, showing improved performance and scalability across 26 cancer types.

bioRxiv · Oct 4, 2019Immunology

Inhaled nicotine equivalent to cigarette smoking disrupts systemic and uterine hemodynamics and induces cardiac arrhythmia in pregnant rats

X. M. Shao, H. E. Lopez-Valdes, J. Liang, J. L. Feldman

This study shows that inhaled nicotine during pregnancy disrupts systemic and uterine hemodynamics and causes cardiac arrhythmia in rats, with effects blocked by a nicotinic receptor antagonist.

bioRxiv · Sep 27, 2017Pharmacology & Toxicology