Author

Xiangwen C Kong

The University of Sydney

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Cancer Biology· 1

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Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

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Anabel Withy· 1 shared Andrew J. HoyiD· 1 shared Lake‐Ee QuekiD· 1 shared Mariam F. Hakeem-Sanni· 1 shared Masih GhasemiiD· 1 shared Nancy T. SantiappillaiiD· 1 shared

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1 shared paperCancer Biology

Anabel Withy

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 25, 2024

Capacity-Contribution Paradox: Fatty Acid Oxidation Compensates for Low Glucose-Derived Acetyl-CoA in Cancer.

Nancy T. Santiappillai, Xiangwen C Kong, Mariam F. Hakeem-Sanni…·Andrew J. Hoy

This study reveals that fatty acid oxidation (FAO) in cancer cells primarily compensates for low glucose-derived acetyl-CoA by supporting mitochondrial metabolism through a malic enzyme-dependent shunt, rather than serving as a primary fuel source.

1 citation

humanmetabolomics

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