Author

Xiangyu Hao

Chinese University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Bao Ting ZhuiD· 3 shared Yi-Chen Jia· 2 shared Yong Xiao YangiD· 2 shared Jialing Zhong· 1 shared Li‐Xi Liao· 1 shared Pan WangiD· 1 shared Qi ZhangiD· 1 shared Tongxiang Chen· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

Bao Ting ZhuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Characterization of the Mechanisms Underlying Sulfasalazine-Induced Ferroptotic Cell Death: Role of Protein Disulfide Isomerase-Mediated NOS Activation and NO Accumulation

Yi-Chen Jia, Jialing Zhong, Xiangyu Hao, Bao Ting Zhu

This study investigates how sulfasalazine induces ferroptosis via PDI-mediated iNOS activation and NO accumulation in rat cell lines.

Acta Biochimica et Biophysica Sinica · Jul 2, 2025Peer-reviewedBiochemistry

Protective Effect of 2-Hydroxyestrone and2-Hydroxyestradiol Against Chemically-Induced Hepatotoxicity In Vitro and In Vivo

Xi Sun, Xiangyu Hao, Yi-Chen Jia, Qi Zhang, Yan-Yin Zhu, Yong Xiao Yang, Bao Ting Zhu

This study shows that 2-hydroxyestrone and 2-hydroxyestradiol protect against ferroptosis in hepatoma cells and acetaminophen-induced liver injury by inhibiting PDI activity and reducing NO, ROS, and lipid-ROS accumulation.

Journal of Pharmacology and Experimental Therapeutics · Nov 30, 2024Peer-reviewedPharmacology & Toxicology

Strong Protection by Bazedoxifene Against Chemically-Induced Ferroptotic Neuronal Death In Vitro and In Vivo

Xiangyu Hao, Yifan Wang, Yong Xiao Yang, Li‐Xi Liao, Tongxiang Chen, Pan Wang, Xiaojun Chen, Bao Ting Zhu

This study shows that bazedoxifene inhibits PDI and protects against chemically-induced ferroptosis in neuronal cells both in vitro and in vivo.

bioRxiv · May 26, 2024 · PreprintNeuroscience