Author

Xiaochen Cui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 1 Approach:graph neural network· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Zhangsheng YuiD· 2 shared Cheng LiuiD· 1 shared Haifeng CheniD· 1 shared Haifeng CheniD· 1 shared Jiahui LiniD· 1 shared Junjie ZhuiD· 1 shared Liu Cheng· 1 shared Taiying Cui· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Zhangsheng YuORCID

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2 papers

Recent·Most cited

ProDualNet: Dual-Target Protein Sequence Design Method Based on Protein Language Model and Structure Model

Liu Cheng, Ting Wei, Xiaochen Cui, Haifeng Chen, Zhangsheng Yu

ProDualNet designs dual-target protein sequences by integrating sequence-structure information from two receptors, showing better recovery and success rates than existing methods.

Briefings in Bioinformatics · Jul 1, 2025Peer-reviewedBioinformatics

AI-Driven Efficient De Novo design of GLP-1RAs with Extended Half-Life and Enhanced Efficacy

Ting Wei, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Taiying Cui, Cheng Liu, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Zhangsheng Yu, Haifeng Chen

This paper designs 10,000 de novo GLP-1RAs using AI, with 60 passing stability, efficacy, and diversity criteria, and two showing extended half-lives and superior efficacy in vivo.

bioRxiv · Mar 26, 2025 · PreprintBioengineering