Distinct and Shared Impacts of Virulence Plasmids on the Phenotype and Transcriptome in Convergent Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae
Mingju Hao, Xiaodi Cui, Liya Feng, Ke Liu, Xiaohong Shi, Tengfei Long, Sarah E. Rowe, Yi-Tsung Lin, Liang Chen
This study removes virulence plasmids from two CR-hvKp strains, showing reduced virulence and fitness but strain-specific transcriptional changes and differential regulatory roles of rmp operons.
Microbiology Spectrum · Jun 9, 2026Peer-reviewedMicrobiology