Liya Feng

Distinct and Shared Impacts of Virulence Plasmids on the Phenotype and Transcriptome in Convergent Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae

This study removes virulence plasmids from two CR-hvKp strains, showing reduced virulence and fitness but strain-specific transcriptional changes and differential regulatory roles of rmp operons.

Emergence of hypervirulent Klebsiella pneumoniae ST111 with a novel virulence plasmid causing pyogenic liver abscess

This study identifies a novel hypervirulent Klebsiella pneumoniae ST111 strain with a unique virulence plasmid causing pyogenic liver abscess, highlighting non-canonical lineages as potential sources of emerging virulence.

pGGTOX: a versatile plasmid platform for recombination-based genome editing across Enterobacteriaceae

pGGTOX enables efficient, marker-free genome editing across Enterobacteriaceae using homologous recombination, with applications in gene deletion, plasmid modification, and CRISPR delivery.