Sarah E. Rowe

This study removes virulence plasmids from two CR-hvKp strains, showing reduced virulence and fitness but strain-specific transcriptional changes and differential regulatory roles of rmp operons.

This study identifies a host-directed adjuvant, KL1, that increases intracellular bacterial energy and sensitizes persisters to antibiotics by modulating host immune responses and reducing reactive species production.

This study shows that calprotectin reduces β-lactam antibiotic efficacy by inactivating bacterial autolysins through zinc sequestration, independent of bacterial growth.