Author

Xiaoting Chen

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genomics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew T. WeirauchiD· 3 shared Emily R. MiraldiiD· 2 shared Akshata N. Rudrapatna· 1 shared Aldo Hernandez-Corchado· 1 shared Alec P. PankowiD· 1 shared Alexander Brechalov· 1 shared Alexander V. BrechaloviD· 1 shared Alexandr BoytsoviD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenomics

Matthew T. WeirauchORCID

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3 papers

Recent·Most cited

Clonal hematopoiesis-associated DNMT3A mutations derepress bivalent Polycomb target genes and enhance macrophage migration

Yuri Lee, Philip K. Farahat, Jennifer Nguyen, Yoshiko Takahashi, Jung-Yeon Lim, Xin Huang, Camille Brzechffa, Marie E. S. Wheeler, Hye-Ju Yang, Jihye Lee, Zachary S. Pope, Daniella Lu, Akshata N. Rudrapatna, Alec P. Pankow, Xiaoting Chen, , Minji Byun

bioRxiv · Sep 25, 2026 · PreprintCell Biology

Codebook: sequence specificity and genomic binding of poorly-characterized human transcription factors

Arttu Jolma, Kaitlin U. Laverty, Ali Fathi, Ally W. H. Yang, Isaac Yellan, Ilya E. Vorontsov, Sachi Inukai, Judith F. Kribelbauer-Swietek, Antoni J. Gralak, Rozita Razavi, Mihai Albu, Alexander V. Brechalov, Zain M. Patel, Vladimir Nozdrin, Georgy Meshcheryakov, , Xiaoting Chen

The paper systematically determines the sequence specificity of 332 poorly characterized human transcription factors, identifying over 4,000 experiments and revealing tens of thousands of new TF binding sites.

bioRxiv · Nov 11, 2024 · PreprintGenomics

Nutrient starvation activates ECM remodeling gene enhancers associated with inflammatory bowel disease risk in fibroblasts

Stefano Secchia, Vera Beilinson, Xiaoting Chen, Zi F. Yang, Joseph A. Wayman, Jasbir Dhaliwal, Ingrid Jurickova, Elizabeth B. Angerman, Lee A. Denson, Emily R. Miraldi, Matthew T. Weirauch, Kohta Ikegami

The paper shows nutrient starvation activates ECM remodeling gene enhancers linked to IBD risk in fibroblasts, suggesting a mechanism for pathological fibroblast activation in IBD.

bioRxiv · Sep 6, 2024 · PreprintGenomics