Alpha-Synuclein co-pathology in Alzheimer's Disease drives tau accumulation
Felix L. Struebing, Xiaoxuan Song, Teodoro De Vecchi, Jeannine Widmann, Federico Fierli, Viktoria Ruf, Qilin Tang, Thomas Arzberger, Sigrun Roeber, Thomas Koeglsperger, Otto Windl, Amir Dehsarvi, Matthias Brendel, Nicolai Franzmeier, Juliane Winkelmann, Jochen Wolfgang Herms
This study shows that alpha-Synuclein co-pathology in Alzheimer's Disease increases tau levels, linking AD and Parkinson's Disease pathogenesis.
bioRxiv · Jan 24, 2025 · PreprintNeuroscience