Author

Xinhai Wan

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

David Avila Ramirez· 1 shared Gabriel M. PagnottiiD· 1 shared Jade M. Moehle· 1 shared Jian H. SongiD· 1 shared Joseph L. KiddiD· 1 shared Leah GuerraiD· 1 shared Lucia Martinez CruziD· 1 shared Marie-Claude C. HofmanniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

David Avila Ramirez

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1 paper

Recent·Most cited

Activating RET Mutations Promotes Osteoblastic Bone Metastases in Medullary Thyroid Cancer

Rozita Bagheri‐Yarmand, Gabriel M. Pagnotti, Joseph L. Kidd, David Avila Ramirez, Trupti Trivedi, Leah Guerra, Zhongya Wang, Lucia Martinez Cruz, Jade M. Moehle, Yaashmin Shiny Jebaraj, Xinhai Wan, Jian H. Song, Roland L. Bassett, Sue-Hwa Lin, Mimi I-Nan Hu, , Theresa A. Guise

This study shows that activating RET mutations in medullary thyroid cancer (MTC) cells promote osteoblastic bone metastases by increasing osteoprotegerin (OPG), which inhibits bone resorption and is linked to poor patient survival.

bioRxiv · Jul 9, 2025 · PreprintCancer Biology