TGR5-mediated Ca2+ signaling in cholangiocytes
Xuanmeng Chen, Amr Al‐Shebel, Thibault Pebrier, Thierry Tordjmann, Olivier Dellis
This study shows that TGR5 activation in cholangiocytes induces both cAMP and IP3-Ca2+ pathways, potentially compensating for CFTR loss in cystic fibrosis.
bioRxiv · Jan 23, 2025 · PreprintPhysiology