Stroke induces early recurrent vascular events by inflammasome-dependent atherosclerotic plaque rupture
J. Cao, S. Roth, S. Zhang, A. Kopczak, M. K. Georgakis, X. Li, A. Dutsch, T. G. Liman, M. Endres, D. Brough, J. P. Green, S. R. Wernsdorf, C. Fürle, O. Carofiglio, J. Zhu, , A. Liesz
This study shows stroke triggers inflammasome-dependent atherosclerotic plaque rupture, leading to recurrent stroke, and identifies DNA-mediated inflammasome activation as a therapeutic target.
bioRxiv · Feb 1, 2023 · PreprintImmunology