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2 papers
Recent·Most cited
P. Stirling, S. Tsai, E. Y.-C. Chang, L.-A. Fournier, J. P. Wells, S. W. Minaker, Y. D. Zhu, A. Y.-H. Wang, Y. Wang, D. G. Huntsman
This study shows that ARID1A loss causes DNA replication stress linked to R-loops and transcription-replication conflicts in human cells.
bioRxiv · Nov 16, 2020Cell Biology
E. Y.-C. Chang, J. P. Wells, S.-H. Tsai, Y. Coulombe, Y. A. Chan, Y. D. Zhu, L.-A. Fournier, P. Hieter, J.-Y. Masson, P. C. Stirling
The paper identifies MRE11-RAD50-NBS1's role in suppressing R-loops at transcription-replication conflicts through non-nucleolytic functions and Fanconi Anemia pathway interactions.
bioRxiv · Nov 17, 2018Cell Biology