Author

Y. Grabovska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Burford· 2 shared A. Mackay· 2 shared K. Kessler· 2 shared S. Temelso· 2 shared V. Molinari· 2 shared A. Carai· 1 shared A. Joshi· 1 shared A. Martin· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Burford

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Medulloblastoma Group 3 and 4 Tumors Comprise a Clinically and Biologically Significant Expression Continuum Reflecting Human Cerebellar Development

D. Williamson, E. C. Schwalbe, D. Hicks, K. A. Aldinger, J. Lindsey, S. Crosier, S. Richardson, J. Goddard, R. Hill, J. Castle, Y. Grabovska, J. Hacking, B. Pizer, S. B. Wharton, T. S. Jacques, , S. C. Clifford

The paper shows medulloblastoma Group3 and Group4 tumors form a transcriptional continuum linked to cerebellar development, with prognostic and molecular implications.

bioRxiv · Jun 9, 2022Cancer Biology

Loss of the H4 lysine methyltransferase KMT5B drives tumorigenic phenotypes by depleting H3K27me3 at loci otherwise retained in H3K27M mutant DIPG cells

K. Kessler, A. Mackay, Y. Grabovska, V. Molinari, A. Burford, S. Temelso, H. Tari, E. Yara-Romero, I. Liu, L. Yu, D. Castel, J. Choudhary, A. Sottoriva, M. Filbin, M. Vinci, C. Jones

The paper shows that loss of KMT5B in DIPG cells depletes retained H3K27me3 loci, leading to transcriptional changes that promote tumorigenesis.

bioRxiv · Jul 19, 2021 · PreprintCancer Biology

Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG

D. Carvalho, S. Temelso, A. Mackay, H. Pemberton, R. Rogers, K. Kessler, E. Izquierdo, L. Bjerke, J. Fazal-Salom, M. Clarke, Y. Grabovska, A. Burford, N. Gene-Olaciregui, J. Boult, V. Molinari, , Hubank

bioRxiv · Dec 29, 2020 · PreprintCancer Biology