Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns
Y. Hatoyama, M. Islam, A. G. Bond, K.-I. Hayashi, A. Ciulli, M. T. Kanemaki
The paper combines AID2 and BromoTag degron systems to enhance protein depletion, demonstrating their effectiveness in suppressing DNA replication by co-depleting ORC1 and CDC6.
bioRxiv · Mar 20, 2024Cell Biology