M. T. Kanemaki

This study shows that depleting lamins B1 and B2 changes chromatin mobility and gene expression through mesoscale-motion dependent mechanisms.

This study identifies TRAIP's role in preventing DNA damage during S-phase by resolving replication-transcription conflicts, leading to cell cycle arrest and senescence upon TRAIP depletion.

The paper introduces a method to visualize two endogenous chromatin loci in living cells using synthetic zinc-finger proteins and frankenbodies, revealing their dynamic association and separation upon cohesin disruption.

This study shows Cyclin A can trigger mitosis through Greatwall or Cyclin B by regulating Cdk1 activity and phosphorylation of mitotic substrates.

This paper improves AID technology by introducing new plasmids and auxinole to control degron-fused protein degradation in human cells.

This study uses optogenetic reconstitution to show that NuMA clusters Dynein-Dynactin to generate cortical spindle-pulling forces through multi-arm interactions.

This study shows Ki-67 and condensins have independent yet cooperative roles in maintaining mitotic chromosome structure through distinct mechanisms.

This study shows that condensin is essential for anaphase chromosome segregation and normal chromosome architecture formation, but not for chromatin compaction during mitosis.