Author
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34 papers
Recent·Most cited
M. I. Katsnelson, Y. I. Wolf, E. V. Koonin
This paper explores analogies between physical principles and biological evolution, suggesting that concepts like frustration and percolation may explain the emergence of biological complexity.
E. V. Koonin, Y. I. Wolf, M. I. Katsnelson
The paper demonstrates that genetic parasites are inevitable due to thermodynamic instability of parasite-free states in replicator systems.
I. Sela, Y. I. Wolf, E. Koonin
The paper refines a mathematical model of microbial genome evolution by incorporating group-specific factors, finding a mean selection coefficient of ~10^-10 and a deletion bias greater than unity.
S. A. Shmakov, V. Sitnik, K. S. Makarova…·E. Koonin
The study analyzes CRISPR spacers across bacterial and archaeal genomes, finding most target mobile genetic elements and showing strong compositional correlations with microbial and viral genomes.