Author

Y. Janardhanan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Song· 2 shared C. Bruedigam· 2 shared J. Straube· 2 shared L. Cooper· 2 shared S. W. Lane· 2 shared A. H. Porter· 1 shared A. P. Sobinoff· 1 shared A. Porter· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Song

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Imetelstat-Mediated Alterations in Fatty Acid Metabolism To Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia

C. Bruedigam, A. H. Porter, A. Song, G. Vroeg in de Wei, T. Stoll, J. Straube, L. Cooper, G. Cheng, V. F. S. Kahl, A. P. Sobinoff, V. Y. Ling, B. M. C. Jebaraj, Y. Janardhanan, R. Haldar, L. J. Bray, , S. W. Lane

This study identifies ferroptosis as a mechanism by which imetelstat induces therapeutic effects in AML, showing that targeting fatty acid metabolism enhances its efficacy.

bioRxiv · Apr 25, 2023Cancer Biology

Oncogenic drivers dictate immune control of acute myeloid leukemia.

R. J. Austin, J. Straube, R. Halder, Y. Janardhanan, C. Bruedigam, M. Witkowski, L. Cooper, A. Porter, M. Braun, F. Souza-Fonseca-Guimaraes, S. A. Minnie, E. Cooper, S. Jacquelin, A. Song, T. Bald, , M. J. Bywater

This study shows that specific AML oncogenes influence immune responses and escape mechanisms, with NrasG12D promoting anti-leukemia immunity that can be counteracted by Myc.

bioRxiv · Feb 8, 2023Cancer Biology