Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity.
J. C. Correia, Y. Kelahmetoglu, P. R. Jannig, C. Schweingruber, D. Svaikovskaya, L. Zhengye, I. Cervenka, M. Oliveira, J. Nijssen, V. Martinez-Redondo, M. Stec, N. Khan, J. T. Lanner, S. Kleiner, E. Hedlund, J. L. Ruas
This paper shows that muscle-secreted neurturin (NRTN) couples muscle oxidative metabolism with slow motor neuron identity, improving exercise performance and motor coordination.
bioRxiv · Mar 31, 2021Physiology