Author

Y. Mandel-Gutfreund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Argoetti· 1 shared A. Gorelik· 1 shared A. Kshirsagar· 1 shared A. Nahar· 1 shared D. Kasiviswanathan· 1 shared D. Lindell· 1 shared D. Tsuboi· 1 shared H. Enav· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

A. Argoetti

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3 papers

Recent·Most cited

Proteasome gene expression is controlled by the coordinated functions of multiple transcription factors

J. E. Gilda, A. Nahar, D. Kasiviswanathan, N. Tropp, T. Gilinski, T. Lahav, Y. Mandel-Gutfreund, S. Park, S. Cohen

The paper shows that multiple transcription factors coordinate proteasome gene expression in response to catabolic stimuli, identifying PAX4 and PALNRF-1 as key regulators.

bioRxiv · Apr 12, 2023Cell Biology

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

A. Kshirsagar, A. Gorelik, T. Olender, T. Sapir, D. Tsuboi, I. Rosenhek-Goldian, S. Malitsky, M. Itkin, A. Argoetti, Y. Mandel-Gutfreund, S. R. Cohen, J. H. Hanna, I. Ulitsky, K. Kaibuchi, O. Reiner

This study shows LIS1 regulates mESCs viability and mechanosensitive properties through RNA-binding interactions with AGO2 and other proteins.

bioRxiv · Mar 8, 2022Cell Biology

Adaptation to sub-optimal hosts is a driver of viral diversification in the ocean

H. Enav, S. Kirzner, D. Lindell, Y. Mandel-Gutfreund, O. Beja

This study shows that viral diversification in marine cyanophages is driven by adaptation to sub-optimal hosts, leading to rapid mutation accumulation and subpopulation formation.

bioRxiv · Feb 7, 2018Evolutionary Biology