Cell BiologybioRxiv
Implications of cholesterol and sphingomyelin in STING phosphorylation by TBK1
K. Takahashi, T. Niki, E. Ogawa…·T. Taguchi
The paper shows that cholesterol and sphingomyelin are required for TBK1-mediated phosphorylation of STING at the TGN, mirroring in vivo conditions.
DOI 10.1038/s41598-021-91562-z