H. Arai

Cell-based assays and comparative genomics revealed the conserved and hidden effects of Wolbachia on insect sex determination

This study uses cell transinfection and comparative genomics to show that Wolbachia strains inducing male killing or feminization affect sex-determining gene splicing in Lepidoptera, while some non-inducing strains also influence sex determination through different mechanisms.

A non-toxic equinatoxin-II reveals the dynamics of sphingomyelin in the cytosolic leaflet of the plasma membrane

The paper uses a non-toxic SM probe to show dynamic SM and cholesterol domains in the cytosolic leaflet of plasma membranes.

Diversity and characteristics of pTet family plasmids revealed by genomic epidemiology of Campylobacter jejuni from human patients in Toyama, Japan from 2015 to 2019

This study analyzes pTet family plasmids in Campylobacter jejuni isolates from Japan, revealing their diversity and resistance gene distribution.

Male-killing-associated bacteriophage WO identified from comparisons of Wolbachia endosymbionts of Homona magnanima

The paper identifies a male-killing-associated bacteriophage WO in Wolbachia strains of Homona magnanima and proposes a mechanism for male-killing evolution.

Distinct Effects of the Male-Killing Bacteria Wolbachia and Spiroplasma and a Partiti-Like Virus in the Tea Pest Moth, Homona magnanima

This study compares the effects of three male-killing microbes in the tea pest moth, showing they use distinct mechanisms to kill male hosts.

Lysosomal vesiculophagy terminates STING signalling

This study identifies lysosomal vesiculophagy as a mechanism for STING degradation, preventing sustained type I interferon response.

Implications of cholesterol and sphingomyelin in STING phosphorylation by TBK1

The paper shows that cholesterol and sphingomyelin are required for TBK1-mediated phosphorylation of STING at the TGN, mirroring in vivo conditions.

Homeostatic regulation of STING by Golgi-to-ER membrane traffic

This study identifies STING as a cargo of Golgi-to-ER transport and shows that impaired retrograde transport due to COPA syndrome mutations leads to STING activation and autoinflammation.

Phosphorylation of Elovl5 changes its substrate preference to synthesize Mead acid in response to essential fatty acid deficiency

Mother-to-embryo vitellogenin transport in a viviparous teleost Xenotoca eiseni

This study identifies vitellogenin transport from mother to embryo in the viviparous teleost Xenotoca eiseni, showing Vtg presence in ovarian tissues and trophotaenia.