Circadian immunometabolic states impart a temporal response to SARS-CoV-2 spike proteins in mammalian macrophages
Sharleen M. Buel, Jayashree Balaraman, Meaghan S. Jankowski, Kim K. Hixson, Y. S. Gao, Young‐Mo Kim, Nathalie Munoz, Jennifer E Kyle, Mary S. Weir Lipton, Carrie Nicora, Paul Piehowski, Scott Baker, Jennifer M. Hurley
This study investigates how circadian rhythms affect macrophage responses to SARS-CoV-2 spike proteins, finding that timing of exposure leads to distinct immunometabolic states.
Microbial Pathogenesis · Jul 20, 2026Peer-reviewedMolecular Biology