Young‐Mo Kim

Metabolites cross the membrane, the transcriptome does not follow: co-localization is required for the cyanobacterial response to a yeast partner

This study shows that cyanobacteria respond to yeast partners only when co-localized, not just through metabolite exchange.

Cell State Transitions Drive Transcriptome-Proteome Alignment in a Minimal Photoautotroph

The paper investigates how cell state transitions in Prochlorococcus marinus MED4 affect transcriptome-proteome alignment through regulatory mechanisms involving RpaB and HimA.

Saprotrophic soil fungus dissolves lithium lepidolite through inositol rescue metabolism

This study shows a soil fungus alters its metabolism to dissolve lithium ore, releasing soluble lithium, and suggests similar strategies may occur in natural microbial communities.

Circadian immunometabolic states impart a temporal response to SARS-CoV-2 spike proteins in mammalian macrophages

This study investigates how circadian rhythms affect macrophage responses to SARS-CoV-2 spike proteins, finding that timing of exposure leads to distinct immunometabolic states.

Overcoming protocatechuate and catechol accumulation in muconic acid production via adaptive laboratory evolution and metabolic engineering in Pseudomonas putida

This paper improves muconic acid production in Pseudomonas putida by overcoming PCA and catechol accumulation through adaptive evolution and metabolic engineering, showing that increased CatA1 expression enhances pathway efficiency.

Intestinal lipid metabolism controls immune response through NHR-68 and gut-brain signaling in C. elegans

This study shows that NHR-68 in C. elegans links intestinal lipid metabolism to immune and behavioral responses through gut-brain signaling.

Phenological stage influences how white lupin (Lupinus albus) root exudate metabolites respond to phosphorus supply

This study shows that phenological stage has a stronger effect on root exudate metabolites in white lupin than phosphorus supply, with phosphorus effects only observed during flowering.

Calorie Restriction Up-regulates Islet PD-L1 Signaling and Decreases the Risk of Auto-immune Diabetes Onset in NOD Mice.

This study shows calorie restriction delays type 1 diabetes onset in NOD mice by enhancing glucose homeostasis and promoting a pro-tolerogenic islet microenvironment through increased PD-L1 expression.

Phosphorus limitation enhances root exudation and mineral bioweathering across diverse soil process domains

This study shows that phosphorus limitation increases root exudation of carboxylates, which enhances mineral dissolution across different soil types.

Optimizing a High Performing Multiplex-CRISPRi P. putida strain with Integrated Metabolomics and 13C-Metabolic Flux Analyses

The paper optimizes a P. putida strain for indigoidine production using 13C-MFA and metabolomics, identifying key metabolic bottlenecks and engineering improvements.