Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan
T. Onuma, Y. Toshitaka, H. Kosakamoto, H. Kadoguchi, T. Kuraishi, T. Murakami, H. Mori, M. Miura, F. Obata
This study shows that specific bacterial peptidoglycans from Acetobacter persici shorten Drosophila lifespan and increase intestinal stem cell proliferation via gut receptors, while also enhancing stress resistance.
bioRxiv · Feb 16, 2023 · PreprintImmunology