Author

H. Kosakamoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Obata· 4 shared M. Miura· 3 shared T. Onuma· 2 shared A. Nakamura· 1 shared H. Aikawa· 1 shared H. Kadoguchi· 1 shared H. Mori· 1 shared H. Tanimoto· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersPhysiology

F. Obata

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Epidermal tyrosine catabolism is critical for metabolic homeostasis and survival against high-protein diets in Drosophila

H. Kosakamoto, M. Miura, F. Obata

The paper shows that Drosophila epidermis upregulates tyrosine catabolism via the AMPK-FoxO axis to adapt to high-protein diets, ensuring metabolic homeostasis and survival.

bioRxiv · Apr 20, 2023 · PreprintPhysiology

Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila

H. Kosakamoto, F. Obata, J. Kuraishi, H. Aikawa, R. Okada, J. N. Johnstone, T. Onuma, M. D. W. Piper, M. Miura

This study shows that methionine restriction during early adulthood extends lifespan in Drosophila by reducing oxidatively-damaged methionine through MsrA induction.

bioRxiv · Mar 15, 2023 · PreprintPhysiology

Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan

T. Onuma, Y. Toshitaka, H. Kosakamoto, H. Kadoguchi, T. Kuraishi, T. Murakami, H. Mori, M. Miura, F. Obata

This study shows that specific bacterial peptidoglycans from Acetobacter persici shorten Drosophila lifespan and increase intestinal stem cell proliferation via gut receptors, while also enhancing stress resistance.

bioRxiv · Feb 16, 2023 · PreprintImmunology

The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

Y. Yoshinari, H. Kosakamoto, T. Kamiyama, R. Hoshino, R. Matsuoka, S. Kondo, H. Tanimoto, A. Nakamura, F. Obata, R. Niwa

This study identifies Neuropeptide F (NPF) in Drosophila as a sugar-responsive incretin-like hormone that regulates lipid metabolism via glucagon-like and insulin-like hormones.

bioRxiv · May 17, 2021Physiology