Author

Y. van Kooyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Rodriguez· 2 shared F. Chiodo· 2 shared A. Kraneveld· 1 shared A. Molinaro· 1 shared A. Silipo· 1 shared D. A. Stolk· 1 shared D. Garcia-Rivera· 1 shared D. Lindijer· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. Rodriguez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The transcriptional landscape of glycosylation-related genes in cancer

E. Rodriguez, D. Lindijer, S. J. van Vliet, J. J. Garcia-Vallejo, Y. van Kooyk

This study analyzes glycosylation-related genes across multiple cancers, identifying potential biomarkers and showing how cancer cell glycosylation profiles vary by tumor type and clinical outcome.

bioRxiv · Sep 28, 2022Cancer Biology

Human Milk Oligosaccharide 2'-fucosyllactose inhibits ligand binding to C-type lectin DC-SIGN but not to Langerin

R. Mukherjee, V. J. Somovilla, F. Chiodo, S. Bruijns, R. J. Pieters, J. Garssen, Y. van Kooyk, J. v. BERGENHENEGOUWEN, A. Kraneveld

This study shows that 2'-fucosyllactose (2-FL) inhibits DC-SIGN ligand binding but not Langerin, with molecular dynamics revealing structural differences in binding modes.

bioRxiv · Jul 27, 2022Biochemistry

Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 Spike Protein to Host Lectins and Lung Microbiota

F. Chiodo, S. C. M. Bruijns, E. Rodriguez, R. J. E. Li, A. Molinaro, A. Silipo, F. Di Lorenzo, D. Garcia-Rivera, Y. Valdes-Balbin, V. Verez-Bencomo, Y. van Kooyk

This study identifies ACE2-independent carbohydrate-binding interactions of SARS-CoV-2 spike protein with immune lectins and lung microbiota glyco-conjugates, revealing new pathways for viral infection and immune response.

bioRxiv · May 13, 2020 · PreprintImmunology

Comparison of intradermal injection and epicutaneous laser microporation for anti-tumor vaccine delivery in a human skin explant model

S. Duinkerken, J. Lubbers, D. A. Stolk, J. Vree, M. Ambrosini, H. Kalay, Y. van Kooyk

This study compares intradermal injection and laser microporation for anti-tumor vaccine delivery in human skin explants, finding that intradermal injection is more effective for T-cell activation.

bioRxiv · Dec 5, 2019 · PreprintImmunology