Y. Yuzenkova

Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase

This study presents the structure of Si3, a unique insertion in cyanobacterial RNA polymerase, and shows it does not affect catalytic activity despite large motion.

A SI3-sigma; arch stabilizes cyanobacteria transcription initiation complex

The paper reports cryo-EM structures of cyanobacterial transcription initiation complexes and identifies an SI3-{sigma} arch that stabilizes the RNAP-promoter DNA open complex, essential for transcription initiation.

Metabolic cofactors act as initiating substrates for primase and affect replication primer processing

The paper shows that metabolic cofactors are used by primase to initiate RNA primer synthesis and affect primer processing during DNA replication.

RNA polymerase active centre compensates for the absence of transcription proofreading factors in Cyanobacteria

The paper investigates how cyanobacteria compensate for lacking transcription proofreading factors by showing their RNA polymerase actively compensates through structural changes, with trade-offs in regulatory pausing.