Author

Y.-C. Shin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Xu· 2 shared K. Song· 2 shared M. Liao· 2 shared A. Djurabekova· 1 shared A. M. Plummer-Medeiros· 1 shared A. Mungenast· 1 shared C. Bennett· 1 shared D. Qian· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

C. Xu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis of respiratory complexes adaptation to cold temperatures

Y.-C. Shin, P. Latorre-Muro, A. Djurabekova, O. Zdorevskyi, C. Bennett, N. Burger, K. Song, C. Xu, V. Sharma, M. Liao, P. Puigserver

This study identifies a cold-induced conformation of respiratory complex CI:III2 using cryo-EM and simulations, revealing structural changes that enhance electron transfer efficiency in cold environments.

bioRxiv · Jan 16, 2024 · PreprintCell Biology

The crystal and cryo-EM structures of PLCγ2 reveal dynamic inter-domain recognitions in autoinhibition

Y.-C. Shin, A. M. Plummer-Medeiros, A. Mungenast, H.-w. Choi, K. TenDyke, X. Zhu, J. Shepard, N. Zhuang, L. Hu, D. Qian, K. Song, C. Xu, J. Wang, S. B. Poda, M. Liao, Y. Chen

The paper determines crystal and cryo-EM structures of PLCγ2 in autoinhibited states and bound to FGFR1 kinase domain, revealing dynamic inter-domain interactions in autoinhibition.

bioRxiv · Sep 7, 2023 · PreprintBiochemistry

Structural basis for auto-inhibition and activation of a short prokaryotic Argonaute associated TIR-APAZ defense system

L. Guo, P. Huang, Z. Li, Y.-C. Shin, P. Yan, M. Lu, M. Chen, Y. Xiao

The paper determines cryo-EM structures of SPARTA in different states to elucidate its auto-inhibition and activation mechanisms.

bioRxiv · Jul 12, 2023 · PreprintBiochemistry