Author

Y.-H. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Huang· 3 shared L. Chen· 1 shared R. Marmorstein· 1 shared S. Deng· 1 shared S. M. Gardner· 1 shared Y. Deng· 1 shared Z. Huang· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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3 shared papersBiochemistry

R. Huang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Effects of Oncohistone Mutations and PTM Crosstalk on the N-terminal Acetylation Activities of NatD

Y.-H. Ho, R. Huang

This study investigates how oncohistone mutations and PTMs affect NatD-catalyzed N-terminal acetylation on histone H4/H2A, revealing their regulatory impacts.

bioRxiv · Oct 21, 2021Biochemistry

Novel bisubstrate inhibitors for protein N-terminal acetyltransferase D

Y. Deng, S. Deng, Y.-H. Ho, S. M. Gardner, Z. Huang, R. Marmorstein, R. Huang

This study designs and characterizes potent bisubstrate inhibitors for NatD, showing high selectivity and revealing the enzyme's ordered Bi-Bi mechanism through crystal structures.

bioRxiv · Jan 24, 2021Biochemistry

Development of a continuous fluorescence-based assay for N-terminal acetyltransferase D

Y.-H. Ho, L. Chen, R. Huang

The paper develops a fluorescence-based assay for NatD to identify small-molecule inhibitors, finding two hits from a compound screen.

International Journal of Molecular Sciences · Jan 8, 2021Peer-reviewedBiochemistry