Author

Y.-H. Youm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

V. D. Dixit· 3 shared C. D. Camell· 2 shared E. L. Goldberg· 2 shared I. Shchukina· 2 shared M. Artyomov· 2 shared T. Dlugos· 2 shared A. Bartke· 1 shared A. Lee· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

V. D. Dixit

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ketogenesis restrains aging-induced exacerbation of COVID in a mouse model

S. Ryu, I. Shchukina, Y.-H. Youm, H. Qing, B. K. Hilliard, T. Dlugos, X. Zhang, Y. Yasumoto, C. J. Booth, C. Fernandez-Hernando, Y. Suarez, K. M. Khanna, T. Horvath, M. O. Dietrich, M. Artyomov, , V. D. Dixit

This study shows that a ketogenic diet reduces inflammation and improves outcomes in aged mice infected with a coronavirus, suggesting potential therapeutic benefits for elderly COVID-19 patients.

bioRxiv · Sep 11, 2020 · PreprintImmunology

Dysregulation of adipose ILC2 underlies thermogenic failure in aging

E. L. Goldberg, I. Shchukina, Y.-H. Youm, C. D. Camell, T. Dlugos, M. Artyomov, V. D. Dixit

The paper identifies age-related changes in adipose tissue that reprogram ILC2, leading to impaired cold tolerance in aged mice.

bioRxiv · Sep 8, 2020 · PreprintImmunology

Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis

C. D. Camell, A. Lee, P. Günther, E. L. Goldberg, O. Spadaro, Y.-H. Youm, A. Bartke, G. B. Hubbard, Y. Ikeno, N. H. Ruddle, J. L. Schultz, V. D. Dixit

This study shows aging increases adipose B cells and FALCs via Nlrp3 inflammasome, impairing metabolism, and B cell depletion improves metabolic function in aged mice.

bioRxiv · Apr 13, 2019Immunology