T. Horvath

A novel approach in heart-rate-variability analysis

This paper introduces a novel HRV descriptor using a modified Poincare plot and establishes a master HRV-HR curve for healthy individuals and heart-attack patients.

Mitochondrial fission governed by Drp1 regulates exogenous fatty acid usage and storage

This study shows that mitochondrial fission, regulated by Drp1, influences how cells balance the use and storage of exogenous fatty acids.

DRP1 IS REQUIRED FOR AGRP NEURONAL ACTIVITY AND FEEDING

This study shows that Drp1 is essential for AgRP neuron activity and feeding by regulating mitochondrial fission and fatty acid utilization.

Ketogenesis restrains aging-induced exacerbation of COVID in a mouse model

This study shows that a ketogenic diet reduces inflammation and improves outcomes in aged mice infected with a coronavirus, suggesting potential therapeutic benefits for elderly COVID-19 patients.

The mammalian CLU homolog FMT controls development and behavior in Arabidopsis

This study shows that the Arabidopsis FMT gene, a homolog of mammalian CLU, affects plant development and behavior under stress and controls mitochondrial dynamics and growth traits.

Neuroinvasion of SARS-CoV-2 in human and mouse brain

This study investigates SARS-CoV-2 neuroinvasion in human and mouse brains using organoids, in vivo models, and autopsies, finding evidence of neuronal infection and its consequences.

Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

This study shows oral WR-2721 provides effective radioprotection and survival benefits after lethal radiation by selectively protecting the intestine.