Mouse Norovirus infection arrests host cell translation uncoupled from the stress granule-PKR-eIF2α axis
S. Fritzlar, T. Aktepe, Y.-W. Chao, M. McAllaster, C. Wilen, P. White, J. Mackenzie
This study shows that mouse norovirus infection suppresses host translation and cytokine production while promoting viral replication by recruiting G3BP1 to block stress granule formation.
bioRxiv · Jan 31, 2019Microbiology