Author

Yaeko Long

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Akosua BusiaiD· 1 shared Cristal AquinoiD· 1 shared Cynthia I. TerraceiD· 1 shared David F. SavageiD· 1 shared Hunter M. NisonoffiD· 1 shared Jennifer ListgarteniD· 1 shared Luke M. OltroggeiD· 1 shared Maria LukarskaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Akosua BusiaORCID

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1 paper

Recent·Most cited

Activity and specificity trade-offs in adenine base editors

Maria Lukarska, Luke M. Oltrogge, Hunter M. Nisonoff, Yaeko Long, Cynthia I. Terrace, Akosua Busia, Cristal Aquino, Shineui Kim, Jennifer Listgarten, David F. Savage

This study investigates the trade-off between activity and specificity in adenine base editors using machine learning and high-throughput screening, finding that activity is the primary determinant of editing outcomes.

bioRxiv · Jul 22, 2026 · PreprintMolecular Biology