Microglia replacement effectively attenuates the disease progress of ALSP in the mouse model and human patient
Jingying Wu, Yafei Wang, Xiaoyu Li, Yuanyuan Cai, Pei Ouyang, Yang He, Mengyuan Zhang, Xinghua Luan, Yuxiao Jin, Taohui Liu, Yuxin Li, Xiao‐Jun Huang, Ying Qing Mao, Yanxia Rao, Li Cao, Bo Peng
This study shows that microglia replacement through bone marrow transplantation halts disease progression in both mouse models and human patients with ALSP.
bioRxiv · Jun 11, 2024 · PreprintNeuroscience